Opportunity Information: Apply for RFA DA 25 026
The HEAL Initiative: JCOIN Phase II Community Engaged Research Resource Center (U24 Clinical Trial Optional) is a National Institutes of Health (NIH) cooperative agreement funding opportunity that supports a centralized, community-engaged resource center for the Justice Community Opioid Innovation Network (JCOIN). The overall purpose is to strengthen how research gets translated into real-world practice in criminal-legal settings, with a specific focus on expanding access to evidence-based medications for opioid use disorder (MOUD) for people who are incarcerated or otherwise involved in the justice system. The opportunity is rooted in a well-documented public health problem: people in jails and prisons experience substance use disorder (SUD) and opioid use disorder (OUD) at much higher rates than the general population, face a serious risk of acute opioid withdrawal when they are detained, and are at heightened risk of fatal overdose after release, especially when they have not been offered MOUD while incarcerated. Despite the evidence supporting MOUD, many U.S. jails still do not offer it universally to individuals who could benefit.
This funding opportunity sits within the HEAL (Helping to End Addiction Long-term) Initiative and is described as the only HEAL effort with a primary focus on justice-involved populations and criminal-legal systems. JCOIN itself is positioned as a research-to-practice network that aims to address the overdose crisis by increasing delivery of and access to MOUD in justice contexts. The broader JCOIN portfolio includes hybrid effectiveness-implementation trials, meaning projects are designed to test both whether interventions work and how to implement them effectively under real-world constraints. Within that ecosystem, the Phase II Community Engaged Research Resource Center is intended to function as shared infrastructure that helps JCOIN projects and partners overcome common barriers, improve coordination, and support consistent, high-quality community engagement so that research findings and implementation strategies can be adopted and sustained in jails, prisons, courts, probation/parole systems, and related community reentry environments.
Administratively, the award uses a cooperative agreement mechanism (U24), which typically means NIH expects substantial scientific or programmatic involvement during the project period compared to a standard grant. The activity area is listed under Education and Health, and the notice indicates that clinical trials are optional, allowing applicants to propose work that may or may not include a clinical trial component depending on the aims. The funding opportunity number is RFA-DA-25-026, and the CFDA/assistance listing numbers provided are 93.279 and 93.399. The original closing date is January 22, 2025. The award ceiling is listed as $750,000, indicating the maximum budget level expected for an individual award under this announcement (with the number of expected awards not specified in the provided source data).
Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
Foreign eligibility is restricted in the usual NIH manner for a program focused on U.S. justice settings. Non-domestic (non-U.S.) entities are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. At the same time, the notice states that foreign components, as defined in the NIH Grants Policy Statement, are allowed, which typically means a U.S. applicant can include certain well-justified foreign collaborations or elements when they are necessary for the project, even though the applicant organization itself must be domestic.
In practical terms, this opportunity is aimed at building and sustaining the kind of shared, community-centered capacity that makes implementation research in justice settings more feasible and impactful. The resource center concept signals an emphasis on partnership with affected communities and justice stakeholders, helping align research activities with the realities of incarceration and reentry, and ensuring that MOUD expansion efforts are not only tested but also positioned to be adopted across diverse criminal-legal environments.Apply for RFA DA 25 026
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "HEAL Initiative: JCOIN Phase II Community Engaged Research Resource Center (U24 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279, 93.399.
- This funding opportunity was created on 2024-06-06.
- Applicants must submit their applications by 2025-01-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQ)
What is this funding opportunity?
The HEAL Initiative: JCOIN Phase II Community Engaged Research Resource Center (U24 Clinical Trial Optional) is a National Institutes of Health (NIH) cooperative agreement that funds a centralized, community-engaged resource center for the Justice Community Opioid Innovation Network (JCOIN).
What is the main purpose of the award?
The purpose is to strengthen how research is translated into real-world practice in criminal-legal settings, with a specific focus on expanding access to evidence-based medications for opioid use disorder (MOUD) for people who are incarcerated or otherwise involved in the justice system.
What problem is this opportunity trying to address?
The opportunity is rooted in the public health challenge that people in jails and prisons experience substance use disorder (SUD) and opioid use disorder (OUD) at much higher rates than the general population, can face acute opioid withdrawal when detained, and have a heightened risk of fatal overdose after release, particularly when MOUD is not offered during incarceration.
Why is MOUD a focus for justice-involved populations?
Despite strong evidence supporting MOUD, many U.S. jails still do not offer it universally to individuals who could benefit. This funding opportunity prioritizes expanding access to MOUD in justice contexts as a key strategy to reduce harm and overdose risk.
How does this opportunity fit within NIH and HEAL?
This funding opportunity sits within the HEAL (Helping to End Addiction Long-term) Initiative and is described as the only HEAL effort with a primary focus on justice-involved populations and criminal-legal systems.
What is JCOIN?
JCOIN (the Justice Community Opioid Innovation Network) is described as a research-to-practice network aimed at addressing the overdose crisis by increasing delivery of and access to MOUD in justice settings.
What is meant by a "Community Engaged Research Resource Center" in this context?
The Phase II resource center is intended to serve as shared infrastructure for JCOIN projects and partners. Its role is to help overcome common barriers, improve coordination, and support consistent, high-quality community engagement so that research findings and implementation strategies can be adopted and sustained in real criminal-legal environments.
What types of justice settings are referenced?
The opportunity specifically mentions jails, prisons, courts, probation/parole systems, and related community reentry environments as settings where adoption and sustainment of MOUD-related research and implementation strategies are relevant.
What kinds of research does the broader JCOIN portfolio include?
The broader JCOIN portfolio includes hybrid effectiveness-implementation trials, meaning projects are designed to test both whether interventions work and how to implement them effectively under real-world constraints.
What activity code and mechanism does this award use?
The award uses a U24 cooperative agreement mechanism.
What does a U24 cooperative agreement imply?
A cooperative agreement typically means NIH expects substantial scientific or programmatic involvement during the project period compared to a standard grant.
Are clinical trials required?
No. The opportunity is labeled "Clinical Trial Optional," meaning applicants may propose work that may or may not include a clinical trial component depending on the aims.
What is the funding opportunity number?
The funding opportunity number is RFA-DA-25-026.
What are the CFDA/Assistance Listing numbers associated with this opportunity?
The CFDA/Assistance Listing numbers provided are 93.279 and 93.399.
What is the application deadline?
The original closing date listed is January 22, 2025.
How much funding is available per award?
The award ceiling is listed as $750,000, which indicates the maximum budget level expected for an individual award under this announcement.
How many awards will NIH make?
The number of expected awards is not specified in the provided information.
What is the listed activity area for this opportunity?
The activity area is listed under Education and Health.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and government entities, including state governments; county governments; city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses.
Are minority-serving institutions specifically included as eligible applicants?
Yes. The announcement highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible?
Yes. The announcement explicitly includes faith-based or community-based organizations among eligible applicant categories.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are included among the eligible applicant categories mentioned.
Are non-U.S. (foreign) organizations eligible to apply?
No. Non-domestic (non-U.S.) entities are not eligible to apply for this opportunity.
Can a U.S. organization include a non-U.S. component?
Non-domestic components of U.S. organizations are not eligible to apply. However, the notice states that foreign components (as defined in the NIH Grants Policy Statement) are allowed, which generally means certain well-justified foreign collaborations or elements may be included when necessary for the project, as long as the applicant organization is domestic.
What is the intended value of creating a centralized resource center for JCOIN?
The resource center concept emphasizes building and sustaining shared, community-centered capacity that makes implementation research in justice settings more feasible and impactful, and helps ensure MOUD expansion efforts are positioned to be adopted across diverse criminal-legal environments.
How does community engagement relate to this award?
Community engagement is a central theme of the opportunity. The resource center is meant to support consistent, high-quality community engagement so that research and implementation strategies align with the realities of incarceration and reentry and are more likely to be adopted and sustained.
What population is this opportunity primarily focused on?
The primary focus is on people who are incarcerated or otherwise involved in the justice system, within criminal-legal settings and related reentry environments.
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| Funding Opportunity |
|---|
| HEAL Initiative: JCOIN Phase II Innovation Hubs (R01 Clinical Trial Optional) Apply for RFA DA 25 062 Funding Number: RFA DA 25 062 Agency: National Institutes of Health Category: Education, Health Funding Amount: $2,250,000 |
| Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional) Apply for RFA CA 24 027 Funding Number: RFA CA 24 027 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Translational Resource Centers to Build Bridges Between Substance Use Epidemiology/Etiology and Prevention Intervention Research (U24 Clinical Trials Not Allowed) Apply for RFA DA 25 040 Funding Number: RFA DA 25 040 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R43/R44 - Clinical Trial Optional) Apply for RFA DA 25 050 Funding Number: RFA DA 25 050 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R41/R42 - Clinical Trial Optional) Apply for RFA DA 25 049 Funding Number: RFA DA 25 049 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and CNS Persistence: Implications in HIV Neuropathogenesis and Cure (R01 Clinical Trial Not Allowed) Apply for RFA MH 25 180 Funding Number: RFA MH 25 180 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and CNS Persistence: Implications in HIV Neuropathogenesis and Cure (R21 Clinical Trial Not Allowed) Apply for RFA MH 25 181 Funding Number: RFA MH 25 181 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional) Apply for PAR 24 238 Funding Number: PAR 24 238 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) Apply for PAR 24 239 Funding Number: PAR 24 239 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Mechanistic Studies to Investigate the Interrelationship Between Sleep and/or Circadian Rhythms and Substance Use Disorders (R01 Clinical Trials Not Allowed) Apply for RFA DA 25 045 Funding Number: RFA DA 25 045 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Mechanistic Studies to Investigate the Interrelationship Between Sleep and/or Circadian Rhythms and Substance Use Disorders (R01 Basic Experimental Studies with Humans Required) Apply for RFA DA 25 044 Funding Number: RFA DA 25 044 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Novel Preclinical Models of NeuroHIV in the cART Era (R61/R33 - Clinical Trial Not Allowed) Apply for RFA NS 24 035 Funding Number: RFA NS 24 035 Agency: National Institutes of Health Category: Education, Health Funding Amount: $600,000 |
| Combined Neuromodulation and Behavioral Treatment Algorithm Development for Stimulant Use Disorder (StUD) Enriched for Vulnerable Phenotype (U01 Clinical Trial Required) Apply for RFA DA 25 057 Funding Number: RFA DA 25 057 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional) Apply for PAS 24 242 Funding Number: PAS 24 242 Agency: National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| Translational Resource Centers to Build Bridges Between Substance Use Epidemiology/Etiology and Prevention Intervention Research (U24 Clinical Trials Not Allowed) Apply for RFA DA 25 085 Funding Number: RFA DA 25 085 Agency: National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| National Cancer Institute Youth Enjoy Science Research Education Program (R25 Clinical Trial Not Allowed) Apply for RFA CA 24 026 Funding Number: RFA CA 24 026 Agency: National Institutes of Health Category: Education, Health Funding Amount: $400,000 |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 24 253 Funding Number: PA 24 253 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Device Based Treatments for Substance Use Disorders (UG3/UH3 Clinical Trial Optional) Apply for PAR 25 023 Funding Number: PAR 25 023 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Translating Socioenvironmental Influences on Neurocognitive Development and Addiction Risk (TranSINDA) (U01 Clinical Trial Not Allowed) Apply for RFA DA 25 037 Funding Number: RFA DA 25 037 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Translating Socioenvironmental Influences on Neurocognitive Development and Addiction Risk (TranSINDA) (U24 Clinical Trial Not Allowed) Apply for RFA DA 25 038 Funding Number: RFA DA 25 038 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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