NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Required) | PAR 22 045

Opportunity Information: Apply for PAR 22 045

The NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Required) is a National Institutes of Health (NIH) career development grant designed to help highly qualified dentist-scientists move from NIH intramural postdoctoral training into independent, externally funded research careers. The central aim is a structured transition: applicants begin in a mentored environment within the NIH Intramural Research Program and then shift to an extramural institution where they can establish themselves as new independent investigators with their own research support. As the title indicates, this particular K22 funding opportunity requires involvement in a clinical trial, meaning the proposed career development and research activities must align with NIH and NIDCR expectations for clinical trial planning, conduct, or related responsibilities as defined by NIH policy.

This opportunity is administered by NIH, specifically the National Institute of Dental and Craniofacial Research (NIDCR), and is offered as a discretionary grant under Funding Opportunity Number PAR-22-045. It falls under the health funding activity category and is associated with CFDA number 93.121. The program is tailored to dentists currently in NIH intramural postdoctoral fellowship positions who are ready to take the next step toward independence, using the award as a bridge from mentored training to a faculty-level or equivalent independent research role at an extramural institution.

A wide range of applicant organizations are eligible to apply for this grant once the candidate transitions to the extramural phase, reflecting NIHs broad extramural ecosystem. Eligible applicants include various levels of U.S. government entities (state, county, city/township, and special district governments), independent school districts, public and state-controlled institutions of higher education, and private institutions of higher education. Eligibility also extends to federally recognized Native American tribal governments, tribal organizations that are not federally recognized, and public housing authorities or Indian housing authorities. In addition, nonprofit organizations (both with and without 501(c)(3) IRS status) may apply when otherwise eligible, as can for-profit organizations (other than small businesses) and small businesses. The announcement also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the announcement draws clear boundaries around foreign participation. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply as applicant organizations. Likewise, non-domestic components of U.S. organizations are not eligible to apply. However, the funding opportunity allows foreign components as defined in the NIH Grants Policy Statement, which generally means a U.S.-based applicant organization may include certain discrete project elements performed outside the United States when scientifically justified and permitted under NIH policy.

Key administrative details from the listing include an original closing date of July 18, 2024, and an opportunity creation date of January 10, 2022. The award ceiling and expected number of awards are not specified in the provided source data, which typically means applicants need to consult the full NIH funding opportunity announcement for budget structure, allowable costs, project period expectations, and any institute-specific caps or guidance.

Overall, this K22 is best understood as a targeted career transition mechanism for dentist-scientists: it is meant to retain and advance talented clinical researchers by helping them carry momentum from NIH intramural mentorship into a stable extramural appointment where they can launch an independent research program, with the added requirement that the supported pathway includes clinical trial-related work consistent with NIH definitions and oversight standards.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121.
• This funding opportunity was created on 2022-01-10.
• Applicants must submit their applications by 2024-07-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 22 045

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