Opportunity Information: Apply for HRSA 21 144

Global Reach II (HRSA-21-144) is a discretionary federal funding opportunity from the U.S. Department of Health and Human Services, Health Resources and Services Administration (HRSA), offered as a cooperative agreement. The program is designed to support work that helps countries and partners move toward sustainable HIV epidemic control, in line with the strategic direction set by the Office of the Global AIDS Coordinator at the U.S. Department of State. A central theme of the opportunity is collaboration: applicants are expected to work jointly with HRSA and other stakeholders to develop and deliver practical, high-quality solutions across a broad range of HIV-related programming needs, with an emphasis on new and innovative approaches rather than business-as-usual implementation.

The initiative focuses not only on delivering services, but also on ensuring that the latest scientific advances in HIV prevention, treatment, and care are translated into real-world programming. In addition, it explicitly recognizes that external shocks, such as global pandemics, can disrupt HIV services and outcomes, and it encourages program designs that help mitigate those disruptions. The scope is intentionally broad, spanning direct health services, structural interventions that address barriers in the environment or system, and stronger data use and tracking systems that can guide decision-making, monitor performance, and improve outcomes over time.

Global Reach II is organized around four major categories of support. First, HIV Direct Service Delivery covers activities that improve access to and quality of HIV prevention, testing, treatment, and related care services. Second, Human Resources for Health targets the workforce side of the response, including strengthening the capacity, distribution, and effectiveness of health workers and teams needed to deliver HIV services at scale. Third, Quality Improvement emphasizes continuous improvement methods and practical approaches that make services more reliable, patient-centered, and effective, often by using routine data and structured improvement cycles. Fourth, Health Systems Strengthening supports the underlying systems that sustain HIV programs, such as governance, supply chains, information systems, service integration, and other cross-cutting functions that determine whether gains can be maintained long term.

The opportunity also notes that Global Reach will leverage HRSA broader expertise in global health needs, suggesting that awardees may be expected to draw on HRSA strengths beyond HIV alone, especially where broader health system capacity affects HIV outcomes. The listing is associated with CFDA (now Assistance Listing) 93.266. The expected number of awards is two. The posted award ceiling is listed as 0, which typically signals that a specific cap was not provided in the summarized field and that applicants would need to consult the full notice for funding levels, budgeting expectations, and any constraints.

From an administrative standpoint, the funding opportunity was created on June 21, 2021, with an original application closing date of July 21, 2021. Eligibility is described as "Others" with clarification referenced in the opportunitys additional eligibility text, meaning applicants would need to review the full announcement to confirm which organizations or entities qualify. Overall, Global Reach II is positioned as a partnership-oriented, innovation-driven effort to improve HIV outcomes through a combination of service delivery support, workforce strengthening, quality improvement, and broader system-building, with a clear intent to keep programs resilient and responsive as new science and new global challenges emerge.

  • The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Global Reach II" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.266.
  • This funding opportunity was created on Jun 21, 2021.
  • Applicants must submit their applications by Jul 21, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for HRSA 21 144

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